Skin Treatment
Rejuran Healer (PN) vs PDRN Injection: Benefits and Costs Compared
Among skin regeneration treatments in Korea, Rejuran Healer (PN) and PDRN injections are two of the most well-known options. Both are derived from salmon DNA and help repair and rejuvenate the skin, but their molecular structure and mode of action differ. As a result, their benefits and duration vary, making it important to choose the right one based on your skin condition and goals.
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What is Rejuran Healer (PN)?
Rejuran Healer uses Polynucleotide (PN), a long-chain DNA substance. Because it remains longer in the skin, PN helps maintain hydration, improve elasticity, and reduce fine lines over time. With a low risk of allergic reaction, it is suitable even for aging or sensitive skin. Patients often report benefits such as improved hydration, smoother skin texture, smaller pores, and relief from dryness.

What is PDRN Injection?
PDRN, also called the salmon injection, is composed of shorter DNA fragments. It is designed to promote tissue regeneration and has been widely used in wound healing, acne scars, burns, and chronic skin damage. By stimulating fibroblast activity and activating growth factors, it helps speed up skin recovery and provides strong anti-inflammatory effects, making it effective for quick results.

PN vs PDRN: What’s the Difference?
Although both PN and PDRN improve skin regeneration, their focus differs. PDRN is absorbed quickly and is better for short-term effects such as wound healing or inflammation reduction. PN, on the other hand, stays longer in the skin, offering long-term hydration, elasticity, and anti-aging results. In summary, PDRN is ideal for fast recovery, while PN is better for ongoing skin improvement.
Category | Rejuran Healer (PN) | PDRN Injection |
---|---|---|
Main Ingredient | Long-chain DNA (Polynucleotide) | Short DNA fragments (Polydeoxyribonucleotide) |
Benefits | Hydration, elasticity, wrinkle reduction, skin barrier repair | Quick healing, anti-inflammatory effects, scar regeneration |
Duration | Long-lasting, remains in skin longer | Rapid absorption, short-term results |
Price (Korea) | ₩250,000–₩400,000 per session | ₩100,000–₩200,000 per session |
Best For | Aging, dry, or sensitive skin; long-term skin improvement | Damaged skin, scars, inflammation relief, quick recovery |
What to Check Before Getting Treatment in Korea
For anyone considering Rejuran Healer or PDRN injections in Korea, it is important to confirm whether the clinic uses authentic products and ensure that a certified dermatologist performs the procedure. The typical Rejuran Healer price in Korea ranges from ₩250,000 to ₩400,000 per session, while the PDRN injection price in Korea is more affordable at ₩100,000 to ₩200,000. Checking Rejuran reviews and PDRN injection reviews on platforms like Naver blogs or Instagram provides insight into real experiences. Package deals and seasonal promotions can also reduce the cost significantly.
Conclusion
Rejuran Healer (PN) is best for long-term skin improvement, hydration, and elasticity, while PDRN is better for fast recovery and anti-inflammatory effects. The choice depends on your skin condition, budget, and treatment goals, and it’s always best to consult a dermatologist to decide which option is right for you.
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